📋1. OVERVIEW & PROTOCOL

• Compound Structure: TB-500 is a synthetic peptide engineered as a functional analogue of Thymosin Beta-4, a water-soluble 43-amino-acid regulatory protein investigated in advanced laboratory settings.
• Biological Focus: Primarily analyzed in cell-culture models to characterize its structural interactions with actin, monomeric G-actin pools, cell-motility cascades, and tissue-remodeling processes.
• Cellular Intensity: In-vitro testing tracks endothelial cell migration, cytoskeletal network dynamics, scratch-wound closure velocity, and targeted angiogenesis-associated signaling pathways.

🧪2. CHEMICAL PROPERTIES

• Chemical Formula: C212H350N56O78S (Conserved Active Region Segment: C38H68N10O14)
• Molecular Molar Mass: 4693.4 g/mol (Active Domain Fragment: 889.02 g/mol)
• CAS Number Reference: 77591-33-4 / 88534-08-9
• Sequence Fidelity: Verified via mass spectrometry (ESI-MS / MALDI-TOF) mapping sequence identity, methionine residue oxidation states, and solid-phase synthesis compliance.
• Reconstitution & Solubility: Meticulously lyophilized as a freeze-dried white powder format; highly soluble in bacteriostatic water solvent systems.
• Storage Protocol: Maintain the solid lyophilized powder format at -20°C shielded from light and moisture. Reconstituted laboratory samples require continuous refrigeration at 2-8°C.

🔬3. AUDITED RESEARCH & SPECIFICATIONS

• Stability Advantage: Engineered with structural resistance against process-related impurities and rapid enzymatic breakdown, providing consistent reference values across diverse rodent-model trial groups.
• Signaling Pathways: Mediates precise cellular drive through the short conserved actin-binding domain commonly designated as the LKKTET-type motif.
• Important Regulatory Notice: This reference material is supplied strictly for laboratory research and in-vitro clinical evaluation purposes. It is not approved by the FDA and is strictly prohibited for human or veterinary use.