•🧬SS-31 for laboratory use only:
Procure a certified synthetic reference standard engineered for selective mitochondrial membrane interaction and cellular bioenergetics research. This specialized tetrapeptide formulation links technical sequence parameters within a single, vacuum-sealed format, helping laboratory settings analyze cellular stress responses and biochemical signaling loops cleanly without baseline shifting.
•⚙️1. Preclinical Handling & Stability
Advanced manufacturing methods secure exceptional structural uniformity inside every reference standard lot number. To protect the primary sequence chains from premature breakdown or cleavage, store the dry lyophilized powder sealed inside your freezer environment at -20°C, keeping the glass vial fully insulated from moisture and direct light. Reconstitute the white compact cake matrix smoothly using proper research solvents or bacteriostatic water under clean laboratory procedures. Reconstituted working liquid stocks require continuous climate control inside refrigerator units at 2-8°C to secure data reproducibility throughout your screening assays. U.S. facility dispatch corridors manage rapid domestic shipping to secure absolute chemical longevity upon arrival.
•🔬2. Research Mechanisms & Preclinical FAQ
•📋What specific biological mechanisms define the cell-permeable MTP-131 architecture?
Preclinical literature monitors this synthetic tetrapeptide arrangement for its high affinity toward cardiolipin, an essential inner-membrane phospholipid. In-vitro models implement the sequence to track downstream mitochondrial membrane potential dynamics, reactive oxygen species readouts, and related oxidative stress endpoints within isolated organelle systems.
•📋How do investigators verify lot-specific transparency before assay execution?
Every reference batch connects directly to its authenticated Certificate of Analysis (COA). Independent testing networks implement reversed-phase high-performance liquid chromatography and mass spectrometry to confirm identity parameters against the expected theoretical mass values, documenting a purity threshold of ≥99% on every lot.
•📊3. Verified Sequence Specifications
| Compound Blueprint: | SS-31 Formulation Reference Standard Presentation |
| CAS Registry Code: | 736992-21-5 (For Strict Analytical Traceability Records) |
| Molecular Formula Base: | C32H49N9O5 (Corresponding to the Elamipretide Component) |
| Expected Molar Mass: | 639.80 g/mol |
| Sequence Architecture: | D-Arg-Dmt-Lys-Phe-NH2 (Dmt = 2',6'-dimethyl-L-tyrosine) |
| Purity Certification: | ≥99% Pure Verified via High-Performance Liquid Chromatography |
99% Purity Guaranteed
Independent Lab Tested
•🎓Preclinical & Scientific References
For verification of the biological mechanisms, mitochondrial membrane localization, and molecular traits cited in current biochemical essays, researchers are encouraged to review the official peer-reviewed literature and trials:
- • Szeto, H. H. (2006). Discovery and development of aromatic-cationic peptides as mitochondrial-targeted antioxidants. The AAPS Journal, 8(3), E521-E531.
- • Birk, A. V., et al. (2013). The cell-permeable tetrapeptide SS-31 binds to cardiolipin and alters inner mitochondrial membrane potential dynamics. Journal of Biological Chemistry, 288(32), 22847-22859.
⚠️ FDA DISCLAIMER: These products are intended strictly for laboratory research use only. They are not intended for human consumption, diagnostic, or therapeutic purposes. The statements on this website have not been evaluated by the Food and Drug Administration.
