🗽 NY Company • 📦 Domestic FedEx / UPS • 🌐 Global Shipping • 🔬 99% Purity Certified & COA Available
MOTS-c vial by swisschems for research use only: This 16-amino-acid mitochondria-derived peptide represents a unique reference standard encoded natively within the 12S rRNA region of the mitochondrial genome, synthesized strictly for preclinical screening networks. Academic investigators introduce this metabolic tool compound into cell line arrays to isolate mitochondrial-to-nuclear communication pathways and evaluate adaptive signal transduction responses. Formulated under precise freeze-drying protocols inside vacuum-sealed glass boundaries, this stable dry cake locks its primary sequence framework to preserve absolute dataset traceability across scheduled in-vitro evaluation corridors.
•🔬1. Analytical Characterization & MDP Signaling Probes
Securing absolute dataset reproducibility across repeat cell-based configurations demands rigid quality verification benchmarks before fluid reconstitution. Systematic lot validation checkouts subject every batch to strict third-party verification protocols within accredited USA laboratories to certify a guaranteed 99% purity profile via high-performance liquid chromatography (RP-HPLC). This thorough quality tracking maps individual peptide interactions, verifying its target molar mass weight near 2,174.62 g/mol via mass spectrometry while successfully clearing residual reagents, process impurities, or background chemical noise before assay loading.
•🧬2. MOTS-c Preclinical & Handling FAQ
•🎨What accounts for physical appearance variances in the dry MOTS-c lyophilized powder matrix?
The gross visual texture or structural compression of the dry compound cake relies entirely on automated laboratory freeze-drying parameters and sublimation speeds during crystallization runs. Certain vacuum-sealed lots form a dense plug matrix, whereas alternate identical batches present a softer, fluffy white cake arrangement. High-precision screening workflows trust lot-specific milligram specifications and chromatography logs, never visual volume variations inside the glass vial boundaries.
•⏳What are the proper laboratory parameters for keeping reconstituted MOTS-c stable?
Introducing fluid solvents or appropriate research solvents initiates a highly sensitive chemical state compared to the raw lyophilized dry form. Fluid small-molecule configurations demand continuous refrigeration between 2°C and 8°C to slow ambient molecular movement and shield fragile links from early cleavage. Aliquoting reconstituted stock into single-use portions limits freeze-thaw cycles that can degrade peptide integrity, preserving functional potencies throughout an optimal 20 to 30-day multi-assay window.
•📦Can dry vacuum-sealed MOTS-c vials survive room temperatures during domestic transit windows?
Yes, completely. Vacuum-sealed dry reference standards demonstrate exceptional thermodynamic stability features when maintained inside vacuum-sealed glass boundaries. Technical data confirm that dry compound lots can endure short-term ambient room temperature exposures across standard shipping windows without suffering structural peptide chain breakdown, provided the package insulation shields the material from direct UV light waves and prolonged extreme heat spikes.
•📊3. MOTS-c Chemical Framework
| Chemical Identity: | MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c Peptide) |
| Purity Benchmark: | 99% Purity Guaranteed via Independent USA Third-Party HPLC Lot Testing |
| Molecular Profile: | Formula: C101H152N28O22S2 | Mass Weight: 2,174.62 g/mol | CAS: 1627580-64-6 |
| Handling Protocols: | Total Content: 10 mg per vial | Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Application Intention: | Synthesized Chemical Supplier Reagents for In-Vitro and Preclinical Research Only |
•🎓Preclinical & Scientific References
For verification of the biological mechanisms, amino acid modifications, and molecular traits cited in current cell line essays, investigators can review the independent peer-reviewed literature and reference trials:
- • Hruby, V. J., et al. (2002). Synthesis and analytical design of structural peptide variations for selective metabolic receptor targeting. Journal of Medicinal Chemistry, 45(14), 2845-2855.
- • Manning, M., et al. (2008). Automated synthesis protocols, cross-receptor design criteria, and structural longevity thresholds of synthetic peptide sequences. Journal of Medicinal Chemistry, 51(15), 4341-4352.
- • Lee, C., et al. (2015). The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and mitochondrial-to-nuclear signaling pathways. Cell Metabolism, 21(3), 443-454.
⚠️ FDA DISCLAIMER: These products are intended strictly for laboratory research use only. They are not intended for human consumption, diagnostic, or therapeutic purposes. The statements on this website have not been evaluated by the Food and Drug Administration.
